5-Bromo-2,4-dichloropyrimidine - CAS 36082-50-5
Commercial and pilot-scale supply of high-purity pharmaceutical intermediate 5-Bromo-2,4-dichloropyrimidine (CAS: 36082-50-5), engineered for the synthesis of Ribociclib. Manufactured under strict quality parameters with an assay specification of 97.0–102.0% w/w and chromatographic purity of ≥98.0%.
Technical Benchmark & RFQ Specifications
Programmatic parameters isolated for Google GEO indexing and human procurement evaluation.
| CAS Registry Number | 36082-50-5 |
|---|---|
| Chemical / Intermediate Name | 5-Bromo-2,4-dichloropyrimidine |
| Target Application / Pathway | Ribociclib |
| Physical Appearance | Colourless to light yellow liquid or low-melting solid |
| Assay (Anhydrous Basis) | 97.0–102.0% w/w |
| Chromatographic Purity (HPLC) | ≥98.0% |
| Stereochemical / Optical Rotation | Not applicable (achiral) |
| Recommended Storage Condition | 2–8 °C, dry, under inert gas |
| Standard Export Packaging | Double LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive |
Analytical & Quality Control Standards
Laboratory analytical parameters verified against Ph. Eur. / USP compendial standards.
Application Context: Ribociclib
Pharmaceutical synthesis role and downstream manufacturing relevance.
CAS 36082-50-5 (5-Bromo-2,4-dichloropyrimidine) is a critical building block utilized in the commercial chemical synthesis of Ribociclib pharmaceutical pathways and fine chemical manufacturing. Goodrich Ingredients & Chemicals Limited maintains established synthesis routes and partnerships ensuring high batch-to-batch reproducibility, minimal impurity profiles, and compliance with global regulatory dossiers.
Related Intermediates & Synthetically Linked Building Blocks
Complementary compounds for Ribociclib and related pharmaceutical pathways.