tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate - CAS 571188-59-5
Commercial and pilot-scale supply of high-purity pharmaceutical intermediate tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate (CAS: 571188-59-5), engineered for the synthesis of Palbociclib / Ribociclib. Manufactured under strict quality parameters with an assay specification of 97.0–102.0% w/w and chromatographic purity of ≥98.0%.
Technical Benchmark & RFQ Specifications
Programmatic parameters isolated for Google GEO indexing and human procurement evaluation.
| CAS Registry Number | 571188-59-5 |
|---|---|
| Chemical / Intermediate Name | tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate |
| Target Application / Pathway | Palbociclib / Ribociclib |
| Physical Appearance | Off-white to light brown solid |
| Assay (Anhydrous Basis) | 97.0–102.0% w/w |
| Chromatographic Purity (HPLC) | ≥98.0% |
| Stereochemical / Optical Rotation | Not applicable (achiral) |
| Recommended Storage Condition | 2–8 °C, protected from light and air |
| Standard Export Packaging | Double LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive |
Analytical & Quality Control Standards
Laboratory analytical parameters verified against Ph. Eur. / USP compendial standards.
Application Context: Palbociclib / Ribociclib
Pharmaceutical synthesis role and downstream manufacturing relevance.
CAS 571188-59-5 (tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate) is a critical building block utilized in the commercial chemical synthesis of Palbociclib / Ribociclib pharmaceutical pathways and fine chemical manufacturing. Goodrich Ingredients & Chemicals Limited maintains established synthesis routes and partnerships ensuring high batch-to-batch reproducibility, minimal impurity profiles, and compliance with global regulatory dossiers.
Related Intermediates & Synthetically Linked Building Blocks
Complementary compounds for Palbociclib / Ribociclib and related pharmaceutical pathways.