2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline - CAS 761440-75-9
Commercial and pilot-scale supply of high-purity pharmaceutical intermediate 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline (CAS: 761440-75-9), engineered for the synthesis of Brigatinib. Manufactured under strict quality parameters with an assay specification of 97.0–102.0% w/w and chromatographic purity of ≥98.0%.
Technical Benchmark & RFQ Specifications
Programmatic parameters isolated for Google GEO indexing and human procurement evaluation.
| CAS Registry Number | 761440-75-9 |
|---|---|
| Chemical / Intermediate Name | 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline |
| Target Application / Pathway | Brigatinib |
| Physical Appearance | Off-white to brown solid (darkens on air exposure) |
| Assay (Anhydrous Basis) | 97.0–102.0% w/w |
| Chromatographic Purity (HPLC) | ≥98.0% |
| Stereochemical / Optical Rotation | Not applicable (achiral) |
| Recommended Storage Condition | 2–8 °C under nitrogen, protected from light |
| Standard Export Packaging | Double LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive |
Analytical & Quality Control Standards
Laboratory analytical parameters verified against Ph. Eur. / USP compendial standards.
Application Context: Brigatinib
Pharmaceutical synthesis role and downstream manufacturing relevance.
CAS 761440-75-9 (2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline) is a critical building block utilized in the commercial chemical synthesis of Brigatinib pharmaceutical pathways and fine chemical manufacturing. Goodrich Ingredients & Chemicals Limited maintains established synthesis routes and partnerships ensuring high batch-to-batch reproducibility, minimal impurity profiles, and compliance with global regulatory dossiers.
Related Intermediates & Synthetically Linked Building Blocks
Complementary compounds for Brigatinib and related pharmaceutical pathways.