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CAS Registry: 50846-36-1
Export Ready • Commercial Lot
CAS 50846-36-1Target Application: RaltegravirHPLC Purity ≥98.0%

2-Amino-2-methylpropanenitrile HCl - CAS 50846-36-1

Commercial and pilot-scale supply of high-purity pharmaceutical intermediate 2-Amino-2-methylpropanenitrile HCl (CAS: 50846-36-1), engineered for the synthesis of Raltegravir. Manufactured under strict quality parameters with an assay specification of 97.0–102.0% w/w and chromatographic purity of ≥98.0%.

Assay (Anhydrous)
97.0–102.0% w/w
HPLC Purity
≥98.0%
Appearance
White to off-white crystalline solid (hygroscopic)
Audit Status
Approved
CAS Registry Number
50846-36-1
2D Structure Model
Advanced Intermediate
Formula: C4H8N2·HClMW: 120.58 g/mol
HPLC ≥98.0%
ISO 9001:2015
Batch CoA Included
Export Commercial Lot
Export Packaging & LogisticsGlobal Shipping
Standard Packaging:Double LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive
Storage Condition:2–8 °C, dry, tightly closed
Dispatch Hubs:Air Cargo Chennai / JNPT Mumbai Sea Port (CIF / FOB / DAP)
Accompanying Dossier:Batch CoA, 1H-NMR, Mass Spectra, HPLC Chromatogram & SDS
Commercial Desk (Excellone / Goodrich)
Phone: +91 9445669777
Email: goodrich3210@gmail.com
GSTIN: 33AAECG9615Q2Z2

Technical Benchmark & RFQ Specifications

Programmatic parameters isolated for Google GEO indexing and human procurement evaluation.

CAS: 50846-36-1
CAS Registry Number50846-36-1
Chemical / Intermediate Name2-Amino-2-methylpropanenitrile HCl
Target Application / PathwayRaltegravir
Physical AppearanceWhite to off-white crystalline solid (hygroscopic)
Assay (Anhydrous Basis)97.0–102.0% w/w
Chromatographic Purity (HPLC)≥98.0%
Stereochemical / Optical RotationNot applicable (achiral)
Recommended Storage Condition2–8 °C, dry, tightly closed
Standard Export PackagingDouble LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive

Analytical & Quality Control Standards

Laboratory analytical parameters verified against Ph. Eur. / USP compendial standards.

FTIR Identification:Concordant with reference standard / authenticated spectrum
¹H NMR Spectrum:Consistent with structure; no unassigned signals >1%
Assay Test Method:Potentiometric titration (USP <541>) or HPLC vs. reference standard
Water Content (KF):≤1.0% w/w
Residual Solvents (ICH Q3C):Each solvent within ICH Q3C (R9) limit; supplier to declare all solvents used
Elemental Impurities (ICH Q3D):Per ICH Q3D risk assessment; any metal catalyst used ≤20 ppm

Application Context: Raltegravir

Pharmaceutical synthesis role and downstream manufacturing relevance.

CAS 50846-36-1 (2-Amino-2-methylpropanenitrile HCl) is a critical building block utilized in the commercial chemical synthesis of Raltegravir pharmaceutical pathways and fine chemical manufacturing. Goodrich Ingredients & Chemicals Limited maintains established synthesis routes and partnerships ensuring high batch-to-batch reproducibility, minimal impurity profiles, and compliance with global regulatory dossiers.

Validated Synthesis RouteImpurity Profile DossierNitrogen-Purged Drum PackingCommercial Campaign Supplies

Related Intermediates & Synthetically Linked Building Blocks

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