Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate - CAS 5909-24-0
Commercial and pilot-scale supply of high-purity pharmaceutical intermediate Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate (CAS: 5909-24-0), engineered for the synthesis of Avanafil. Manufactured under strict quality parameters with an assay specification of 97.0–102.0% w/w and chromatographic purity of ≥98.0%.
Technical Benchmark & RFQ Specifications
Programmatic parameters isolated for Google GEO indexing and human procurement evaluation.
| CAS Registry Number | 5909-24-0 |
|---|---|
| Chemical / Intermediate Name | Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate |
| Target Application / Pathway | Avanafil |
| Physical Appearance | White to light yellow solid / low-melting solid |
| Assay (Anhydrous Basis) | 97.0–102.0% w/w |
| Chromatographic Purity (HPLC) | ≥98.0% |
| Stereochemical / Optical Rotation | Not applicable (achiral) |
| Recommended Storage Condition | 2–8 °C, dry, tightly closed |
| Standard Export Packaging | Double LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive |
Analytical & Quality Control Standards
Laboratory analytical parameters verified against Ph. Eur. / USP compendial standards.
Application Context: Avanafil
Pharmaceutical synthesis role and downstream manufacturing relevance.
CAS 5909-24-0 (Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate) is a critical building block utilized in the commercial chemical synthesis of Avanafil pharmaceutical pathways and fine chemical manufacturing. Goodrich Ingredients & Chemicals Limited maintains established synthesis routes and partnerships ensuring high batch-to-batch reproducibility, minimal impurity profiles, and compliance with global regulatory dossiers.
Related Intermediates & Synthetically Linked Building Blocks
Complementary compounds for Avanafil and related pharmaceutical pathways.