3-(Piperazin-1-yl)-1,2-benzisothiazole - CAS 87691-87-0
Commercial and pilot-scale supply of high-purity pharmaceutical intermediate 3-(Piperazin-1-yl)-1,2-benzisothiazole (CAS: 87691-87-0), engineered for the synthesis of Lurasidone / Ziprasidone. Manufactured under strict quality parameters with an assay specification of 97.0–102.0% w/w and chromatographic purity of ≥98.0%.
Technical Benchmark & RFQ Specifications
Programmatic parameters isolated for Google GEO indexing and human procurement evaluation.
| CAS Registry Number | 87691-87-0 |
|---|---|
| Chemical / Intermediate Name | 3-(Piperazin-1-yl)-1,2-benzisothiazole |
| Target Application / Pathway | Lurasidone / Ziprasidone |
| Physical Appearance | White to pale yellow solid |
| Assay (Anhydrous Basis) | 97.0–102.0% w/w |
| Chromatographic Purity (HPLC) | ≥98.0% |
| Stereochemical / Optical Rotation | α-Anomer / sugar diastereomers: each ≤0.5% by HPLC (Chiral HPLC / HPLC); specific optical rotation: report value (Polarimetry) |
| Recommended Storage Condition | 15–25 °C, protected from light |
| Standard Export Packaging | Double LDPE bags (inner antistatic), in HDPE drum / fibre drum; nitrogen-flushed where air-sensitive |
Analytical & Quality Control Standards
Laboratory analytical parameters verified against Ph. Eur. / USP compendial standards.
Application Context: Lurasidone / Ziprasidone
Pharmaceutical synthesis role and downstream manufacturing relevance.
CAS 87691-87-0 (3-(Piperazin-1-yl)-1,2-benzisothiazole) is a critical building block utilized in the commercial chemical synthesis of Lurasidone / Ziprasidone pharmaceutical pathways and fine chemical manufacturing. Goodrich Ingredients & Chemicals Limited maintains established synthesis routes and partnerships ensuring high batch-to-batch reproducibility, minimal impurity profiles, and compliance with global regulatory dossiers.
Related Intermediates & Synthetically Linked Building Blocks
Complementary compounds for Lurasidone / Ziprasidone and related pharmaceutical pathways.